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Best Medicine
RELEASED·SERIES·EN

Best Medicine

Sun, Jan 4, 2026
  • Comedy
  • Drama
Series · Synopsis

Synopsis

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, and he quickly alienates the town, even though he's all they’ve got.

Trailer

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Where to watch

Streaming on

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  • fuboTV↗
  • YouTube TV↗
  • FOX One Amazon Channel↗
Cast

Top of the call sheet

  • Josh Charles
    Josh Charles
    as Dr. Martin Best
  • Abigail Spencer
    Abigail Spencer
    as Louisa Glasson
  • Josh Segarra
    Josh Segarra
    as Sheriff Mark Mylow
  • Cree Cicchino
    Cree Cicchino
    as Elaine Denham
  • Annie Potts
    Annie Potts
    as Aunt Joan
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Episodes

1 season · 13 episodes

Running · 13 aired
Season 1
13 episodes · 13 aired
▾
  • E1
    Docked
    Aired · Mon, Jan 5, 2026 · 60m

    Brilliant and brusque renowned surgeon Martin Best leaves his lucrative career in Boston to become the general practitioner in the small seaside village of Port Wenn, Maine. One local teacher, Louisa Gavin questions his harsh demeanor, while Martin quickly gets annoyed by the antics of its town locals, all while hiding his debilitating aversion to blood.

  • E2
    Bean There Done That
    Aired · Wed, Jan 14, 2026 · 60m

    After Martin comes face to face with his childhood bully and diagnoses a potentially contagious illness, he is forced to cancel Port Wenn's monthly baked bean supper, angering everyone in the town.

  • E3
    Take Me Out of the Ballgame
    Aired · Wed, Jan 21, 2026 · 60m

    On the eve of Port Wenn High School's baseball team's playoff game, the town is furious with Martin when he accidentally breaks the arm of their star player, who happens to be the son of his high school bully. However, Martin suspects the boy has a more serious condition. Meanwhile, Elaine moves into Martin's waiting room after fighting with her mom, Aunt Sarah rivals with a fan of the opposing team, and Louisa makes a conscious effort to make some female friends.

  • E4
    All the World's Ablaze
    Aired · Wed, Jan 28, 2026 · 60m

    Port Wenn's favorite hunky wilderness survival instructor goes missing after Martin deduces that he desperately needs medical help. Also, the locals are furious with Martin after he calls the health inspector on The Salty Breeze suspecting food poisoning and Elaine decides to skip her mother's wedding to the school principal.

  • E5
    Hello Darkness, My Port Wenn
    Aired · Wed, Feb 4, 2026 · 60m

    While conducting a wellness check on the agoraphobic recluse who controls the town power grid and has stopped taking his meds, Martin's brusque bedside manner ultimately causes a massive town black out. As the townspeople fight for electricity, Martin befriends a young boy who reminds him of himself and Louisa and Mark share a romantic moment in the dark.

  • E6
    Eyewitness Blues
    Aired · Wed, Feb 11, 2026 · 60m

    On the eve of Port Wenn's annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries; Martin is disturbed by Aunt Sarah's lack of attention to her health.

  • E7
    There Might Be Blood
    Aired · Wed, Feb 18, 2026 · 60m

    When Port Wenn puts on their annual "Blood Factory," celebrating the gory horror novel set there, Martin must contain his secret debilitating blood phobia when Louisa gets seriously ill and needs his help.

  • E8
    The Bogfather
    Aired · Wed, Feb 25, 2026 · 60m

    Port Wenn goes into high alert when a corpse is found in the town's bog and Martin's autopsy reveals that he was murdered; Martin's solo investigation trek leads him to a startling discovery about himself.

  • E9
    Doc Martin
    Aired · Wed, Mar 4, 2026 · 60m

    When Martin's parents make a surprise visit, Martin suspects that his father, Robert, who blindsides his sister Sarah with some infuriating news, is experiencing a serious health condition. Also, while trying to avoid the school's forthcoming closure amidst its annual Spirit Week sleepover, Louisa is made acting principal and Martin and Robert must operate together on Mark.

  • E10
    Port Wenn-ings and a Funeral
    Aired · Wed, Mar 11, 2026 · 60m

    After Martin invites Louisa to watch the annual bird migration over Port Wenn, he treats an elderly woman whose hallucinations lead to dire consequences. Meanwhile, Aunt Sarah fumes after the reading of a will leaves her nothing and Martin must perform an emergency procedure on his young friend.

  • E11
    Mind Your Own Buboes
    Aired · Wed, Mar 25, 2026 · 60m

    Port Wenn goes on lockdown when a patient with fleas sparks fears of a plague outbreak and Martin must deal with the town gossip when it revolves around him and Louisa. Also, Aunt Sarah feels betrayed by Greg and George and Louisa has an epiphany.

  • E12
    A Tale of Two Sister Cities
    Aired · Wed, Apr 1, 2026 · 60m

    Martin is skeptical when Port Wenn welcomes an extremely friendly delegation from their sister city in Norway and Louisa visits a specialist who just happens to be Martin's ex. Also, Greg believes that he is pooping little men and Mark exhibits troubling symptoms that warrant an intervention.

  • E13
    Norway No How
    Aired · Wed, Apr 8, 2026 · 60m

    As the furious people of Port Wenn discover the truth about their deal with their Norwegian sister city, Martin must toggle between the potential revelation of his blood phobia, a startling baby delivery and the arrival of his amorous ex. Also, Louisa receives some thought-provoking medical results and Al and Elaine must navigate their uncertain future.