Teresa flees Mexico after her drug-runner boyfriend is murdered. Settling in Dallas, she looks to become the country's reigning drug smuggler and to avenge her lover's murder.
On the series premiere of QUEEN OF THE SOUTH the Mexican drug cartel comes after Teresa Mendoza with a vengeance and she is forced to run and do whatever it takes to survive. Teresa's fate is sealed in the dangerous narco world forever and she has to prove her worth to Camila. Meanwhile, Epifanio gets closer in his hunt. Back in Mexico, Brenda desperately tries to find Teresa and hide from the cartel.
Still reeling from the loss of Guero's (Jon Ecker) and her escape to America, Teresa has to fend for herself and avoids being forced into prostitution by proving her worth to Camila. Epifanio's hunt for Teresa leads him to contact Camila. Meanwhile, in Mexico, Brenda, desperately tries to contact Teresa as she and Tony evade Epifanio's hit men.
Camila sends Teresa on a major drug operation to test her loyalty. When Teresa plays a pivotal role in the pickup, she takes a real step toward being trapped into Camila's dark narco world. Camila enlists Teo, a high-powered lawyer, to help her with first big secretive move into taking over Epifanio's cartel. Meanwhile, Brenda, still on the run, finally makes contact with Teresa, who helps her escape, but not how she expected.
An unexpected and deadly hiccup mars Teresa's first solo drug run, forcing James and Camila to clean up the mess. Teresa soon finds herself in further when one of Epifanio's hitmen, "Batman" (Gerardo Taracena) discovers that she's in Dallas, which also forces Camila to make a risky deal on Teresa's behalf. Meanwhile, Brenda and Tony arrive in Dallas.
Teresa advances her plans after witnessing a horrific incident; and Brenda, who's safely in Dallas, begins assembling a team to help her sell drugs.
Camila, who's deep in debt and short on supply, contemplates giving up Teresa; and Brenda's drug enterprise causes problems between her and Tony.
Camila sends Teresa on a dangerous mission; and Brenda, facing a supply shortage, puts her crew in the line of fire.
Camila attempts a risky heist; and Teresa is forced to make a life-changing decision while undercover.
Teresa tries to save a witness to the heist; and a confident Camila vows that she's back in business and is done with Epifanio.
Camila returns to Mexico in order to protect herself; James hunts Teresa; and Teresa faces danger while taking Maria through the tunnel to Mexico.
Camila's operation goes underground when James finally sets out to kill "The Birdman" (Brent Smiga) in a strategic move to align with the Jimenez Cartel. Fed up, Brenda finds herself caught in the crossfire of an escalating drug cartel war. Meanwhile, Epifanio struggles to keep his campaign moving while dodging public rumors of his link to the drug trade violence.
Out of options, Teresa and Brenda find themselves in a desperate situation, playing a dangerous extortion game. Camila sends James on a deadly mission.
Teresa, determined to escape and save Brenda, risks her life to protect the book by any means necessary. Meanwhile, in his campaign for Governor, Epifanio obtains new intel that changes everything.
Teresa brokers a deal with an eccentric smuggler; Camila struggles to rebuild her empire; Epifanio takes on a new partner he may not be able to control.
Old enemies and old flames threaten to tear everything apart when Teresa and crew rig a high-stakes narco horse race.
On a mission to destroy Epifanio's drug smuggling tunnels, Teresa and James come face-to-face with a group of American border vigilantes.
Teresa's loyalties are tested when she is ordered to hunt down and kill a DEA mole.
Teresa, James and Guero travel to Bolivia in search of a new supplier: the mysterious and dangerous narco-cult leader El Santo.
Captured by narco-cult leader El Santo, Teresa embarks on a spiritual journey with real-world consequences.
With the deadline for El Santo's payment looming, Teresa and Camila must find a new distributor—but familiar enemies threaten to derail their plans.
Camila sends Teresa and her crew to Chicago to secure a meeting with an elusive drug distributor.
An uncharacteristic blunder forces Camila and Teresa to go on the run from hit men, but as they flee, their bond grows deeper.
When Teresa competes with James for Camila's trust, she begins to question everything; Epifanio plans to leave the cartel world for good.
Teresa goes on the run from Camila, but after a violent showdown with some hired guns, she realizes that the time for running is over. Now it's time for war.
Determined to break away from Camila for good, Teresa forges new, uneasy alliances -- and for the first time, she brings the fight to Camila's doorstep.
Destinies and desires collide in a final showdown between Teresa and Camila, forcing them to accept one absolute truth: there can only be one queen.
Hiding from Camila in Malta, Teresa tries to launch a drug empire of her own by striking a deal with a dangerous money launderer.
On the run from hitmen in Malta, Teresa is helped by an old friend, whose intentions are anything but clear.
Teresa puts her life and her empire on the line when she attempts to rescue girls being trafficked by her new European business partner.
Teresa flees Europe and starts fresh in Phoenix, Arizona, where she must deal with a commission of cartel bosses and a corrupt local sheriff.
An old enemy lays siege to Teresa's new Phoenix winery, and in defending her business she finds passion with an old friend.
Teresa tries to escape her captors with the help of an unexpected ally.
Rocked by a deeply personal tragedy, Teresa battles a dangerous sicario and a mutiny within her own ranks.
In a bold plan to take over all drug distribution in Phoenix, Teresa makes a deal with the devil.
To help wipe out her rivals in Phoenix, Teresa gets into bed with an ambitious politician.
Returning to Bolivia, Teresa risks her life to prove her loyalty to El Santo.
Teresa hunts for a mole inside her own operation, and faces a terrible choice.
Teresa tries to free a friend from his cage and comes face to face with her sworn enemy.
Reeling from a surprise attack, Teresa makes a bold move to seize the throne.
Teresa expands her business and proves herself to a smuggler who offers her a business opportunity.
Teresa's deal with a smuggler goes sideways when a local kingpin discovers she's smuggling cocaine
A corrupt judge wants in on Teresa's deal when he learns about her business.
While Javier and Boaz deal with a personal problem, Teresa gets involved in a deadly turf war.
El Gordo introduces Teresa to Russian drug queenpin Oksana in the hopes of forging a partnership.
Dealing with the losses of a drug war, Teresa and Dumas finally strike a truce.
On her day off, Teresa is hunted by a sicario from her previous life while on the road.
An FBI informant threatens Teresa's growing empire while she deals with turmoil within her family.
Teresa must choose between leaving New Orleans and compromising her morals.
Teresa works to ease tensions between her business partners after she discovers that someone is stealing from her.
Teresa's closest allies must make difficult decisions without her when she cannot.
Teresa takes out a group of mercenaries while expanding her empire to an unexpected place.
Teresa must solidify a new business deal to take down an enemy - but an unexpected visitor arrives.
Teresa sets out to expand her business in New York City while James proves his allegiance to Teresa.
With tensions rising, Teresa arranges a sit-down in New York between the Dominicans and the Russians.
After the Judge places a bounty on Dumas's head, Teresa sends James to rescue him.
With the Judge dead and Dumas behind bars, Teresa finds herself in the crosshairs of the FBI.
Teresa travels to Germany after Oksana gets cheated in a drug deal.
Teresa solidifies her European foothold while George makes a discovery about Boaz's Miami operation.
Boaz makes moves to dismantle the Mendoza Cartel once and for all.
After Teresa puts her life on the line for Pote and Kelly Anne, the war with Boaz intensifies.
Pote and Kelly Anne adapt to suburban life; Teresa and James are forced to go after Kostya.
Pote, Kelly Anne and James try to disappear, but must fend off attacks from Devon Finch and Boaz.
