When over-the-top Amy enters Allison’s organized but imperfect life and claims to be her guardian angel, they form an unlikely friendship and Allison can’t be sure if Amy is actually an angel or just nuts.
Allison, a successful, driven doctor, runs into Amy, a larger than life, eccentric woman who claims to be her "guardian angel," and whose mission is to help Allison loosen up and see her life from a new perspective:
Allison asks New Kids On The Block favorite Joey McIntyre to help her patch up a relationship with an old friend as part of a lesson Amy's trying to teach her about facing her fears.
Allison takes Amy to a nightclub to help her stop over-thinking everything and let loose, while Marv, suspicious of his daughter's odd new friend, does a background check on Amy.
When Allison tries to convince Marv to make some changes at their dermatology practice, he balks at what she has planned. As a result, Amy takes it upon herself to create a temporary job at the office to help them work things out.
Amy's plan to get Allison to stop caring about "looking stupid" backfires when Allison makes a spontaneous decision that leads her to meet her soulmate before she's supposed to.
Amy is required to perform 10 good deeds to earn her angel powers back after losing them by cheating at a game.
Amy must play guardian angel to both Allison and Brad after Allison accidentally kills Brad's angel, a honey bee.
When Allison is struck with dating jitters, Amy suggests she have a fling to work out her nerves.
When Allison begins dating a new guy, Amy tries to finagle their first kiss before the "window of opportunity" closes to turn things into a lasting relationship.
When Allison reveals how stressful Thanksgiving was after the loss of her mother, Amy suggests a "Funsgiving" instead, with games and untraditional food.
When Amy doesn't have enough money to pay her rent, Allison helps her find a job.
Allison and Amy accidentally record a conversation about guardian angels on Marv's answering machine and try to erase it before he hears it.
Amy getting hit by a bus and then trying to break up Allison's friend's wedding in order to put Allison's future on track.
