
Inspired by actual cases and experiences, Numb3rs depicts the confluence of police work and mathematics in solving crime as an FBI agent recruits his mathematical genius brother to help solve a wide range of challenging crimes in Los Angeles from a very different perspective.






While chasing a serial rapist, FBI Agent Don Eppes gets help from his brother Charlie, who is applied mathematics professor at California Institute of Science. Using his mathematical genius, Charlie attempting to calculate the "hot zone", an area, where the suspect is most likely to live.
After a series of bank robberies, Don recruits Charlie to help chart the next robbery location, only to overlook the thieves' true motive.
Don relies on Charlie's mathematical insight to help stop a virus that has been killing innocent people in Los Angeles.
Charlie convinces Don to investigate a student's suicide in order to make sure that it was not murder.
Don needs Charlie's help to find out why the daughter of a mathematician is kidnapped.
While consulting with the National Transportation Safety Board at the scene of the wreck, Don learns that this tragedy is one of a series of recreated accidents involving railroad negligence. As is the pattern with the previous train wrecks, an undecipherable numerical code is left at the site, which Don recruits Charlie to solve. By breaking the code, Charlie is able to establish that this accident was a recreation of a deadly wreck that left only one survivor several years ago. Don's investigation leads him and his team to a dangerous standoff with their suspect, who has surprising ties to the railway system.
After two teens are found murdered, the investigation leads Don and his team to uncover a dangerous counterfeit money ring.
When new information on an old case comes to light, Don thinks he may have sent the wrong person to jail.
Don and his team must stop a sniper who goes on a killing spree in Los Angeles.
Don and his team are called when it is discovered that a truck driver and his big rig carrying radioactive material have been hijacked and are now missing. They are pressed for time to find the truck when the hijackers threaten to detonate a dirty bomb in an undisclosed location in Los Angeles if they don't receive $20 million in 12 hours.
After an independent computer researcher with a contract with the Defense Department is found murdered, Don and his team are called in to find out who is responsible. After Don recruits Charlie to decode the murder victim's cryptic computer data, Charlie uncovers he was working on a secret and potentially damaging project, forcing Charlie to question the impact of his own life's work.
When a UFO is spotted dangerously close to Los Angeles, Don recruits Charlie to help locate the mysterious aircraft's point of origin and is surprised when it turns into a murder investigation.
As Don investigates the prison bus crash, Charlie uses of probability analysis to conclude that the bus crash was not an accident, but part of a conspiracy to free a dangerous killer. Now, Don and Charlie must discover the killer's lethal agenda and stop him before he is able to carry it out.
Don uses Charlie and Megan's expertise when the FBI is called to the scene of a federal judge's wife's murder.
Don and his team must find who is responsible for kidnapping the family of a jewelry store owner before they are killed.
Don and his team search for the stalker of a pop princess which turns into a murder investigation of a paparazzo.
Don and his team must solve the murder of a CFO of a large energy corporation who is found murdered on her doorstep and her young son is the only witness.
Don and his team find a suspicious code during a raid which Charlie determines is part of a secret plan to assassinate a Colombian exile living in Los Angeles.
Don and his agents must uncover who interfered with a counter-terrorism exercise before deadly results occur.
When a father is killed in a home robbery, Don and his team investigate the connection between several recent robberies in the upscale community.
Routine drug bust unveils a sensitive issue which Charlie takes to heart.
Former chemist of a large pharmaceutical company is discovered to be tampering with medication and Don and Megan must track him down.
The murder of a young museum researcher/archaeologist sends the team on a search for her killer and the missing American Indian skull that she was studying.
Don and his team must find the serial arsonist responsible for an innocent man's death.
When a fellow FBI agent working undercover is killed in a gang retaliation, Don and his team must investigate.
Murder of a young student at a card club leads the FBI to uncover a deadly card counting scheme.
The agents must stop an organ trafficking ring when they discover a young immigrant girl died while selling one of her kidneys.
Cal Sci science student becomes the suspect when an expensive piece of equipment is stolen from the school's DNA lab.
An anti-war bombing which kills an innocent man becomes personal when the investigation reveals surprising information about Don and Charlie's father's past.
When a psychic leads authorities to a deadly crime scene, Charlie sets out to prove it is just a fluke.
The FBI investigates the murder of a female Iraqi activist which happened on U.S. soil.
Don and his team investigate a school shooting only to be surprised with one of the suspects.
Don takes a deeper look at his life after he investigates the circumstances surrounding an ex-girlfriend's death.
When an assailant storms the FBI office with a gun, Charlie gets caught in the crossfire between the suspect and the FBI agents.
Don and his family are in danger when they become the targets of the suspects Don and the team are investigating.
Don enlists Charlie's help when the bodies of five young Asian girls found washed up are suspected of being infected with the Avian influenza virus.
Don and his team must stop a suspected serial killer who drugs and kills young women.
While Don and his team are faced with trying to capture a 30-year-old teacher and her 17-year-old boyfriend/student who are on a violent cross-country crime spree, one of their own gets caught in the crossfire.
Desperate to rescue their fellow agent, Don and his team close in on finding Megan, who is being held hostage by a disturbed teacher on a vicious crime spree.
When a painting worth millions of dollars is stolen from a museum just before it is to go on tour, Don and his team must track down the thief, believing it is part of an insurance scam.
When an interpreter working for the Chinese consulate is killed in an apparent hit and run accident, Don and his team uncover an unlikely connection to the Department of Justice.
Don and his team must determine if a shooting on the freeway was a random act of violence or the work of a serial killer preying on the citizens of Los Angeles.
When Don and his team investigate a murder at a horse track, they stumble onto more than just a plot of betting on fixed races.
When a series of blackouts occur in power stations leaving Los Angeles in the dark, Don and his team must determine if it is an accident or the work of terrorists.
Don and his team investigate the death of a minor league baseball player to determine if it was an accidental overdose of steroids or a homicide.
Don and his team investigate a trail of illegal waste disposal after a sinkhole, which collapses in a school playground, kills an elderly woman and injures several children.
During the murder investigation of a state senator, Don and his team discover a plot to exact revenge on the individuals involved in a government sponsored behavior modification project.
Don and Charlie try to catch a serial killer who is seeking revenge against Internet sexual predators who prey on young girls they meet in chat rooms. Larry launches on a mission to the International Space Station on NASA's Space Shuttle.
Don and his team search for the fundamentalist leader of a polygamous sect who is on the FBI's most wanted list for committing numerous crimes, including rape and murder.
When a multi-million dollar racing yacht sinks during a race, Don and his team are called to investigate after the treasure hunt to find the wreckage turns deadly.
Don and his team investigate a rash of deadly restaurant robberies.
Don and the FBI re-open a 17-year-old unsolved case when the badge of a missing LAPD officer, who is presumed dead, is found at a construction site.
When a competitive mixed-martial arts fighter dies suspiciously in the ring while training for a championship match, the victim's sparring partner, who also happens to be friends with David, becomes the prime suspect.
While Don is unreachable at a therapy session, the FBI and Charlie try to find the son of a music mogul whose kidnapper threatens to kill the boy if he is not paid a multi-million dollar ransom in one hour.
Charlie tries to connect a series of murders to a voter fraud conspiracy and must track down who benefits the most from the rigged elections before more people die.
When a small plane mysteriously crashes, Charlie tests the flight computer and uncovers the truth behind what brought the plane down.
While on the hunt for a serial letter bomber, Don and Charlie disagree over whether a suspected bomber, who had eluded conviction years earlier, is the person responsible for the latest murder.
Don believes that a death row inmate has an ulterior motive when he suddenly wants to confess the whereabouts of bodies he buried during his days as a hit man for the mob.
Don and the FBI uncover a possible terrorist attack on Los Angeles that targets the city's water supply.
When thieves hijack a truck filled with valuable medical supplies, $50 million dollars intended for a relief effort in Zambia and two aid workers, the FBI races a second violent crew intent on getting to the goods first.
In the wake of a deadly standoff with a mysterious, yet, brilliant bomber, Don and Charlie discover that he was poisoned to keep him from exposing a shocking secret that will change the FBI team forever.
Agent Colby Granger lands in prison after the discovery that he was a mole within the FBI, but he escapes, and it's up to Don and his team to track him down and uncover the truth.
Series of secrets and blackmail involving a young, up and coming actor are exposed when Don and his team investigate the murder of a young woman in his Hollywood Hills mansion.
Typical morning at a coffee shop turns into a nightmare when a car collides into it, leaving one person dead and many injured. But what appears to be a car's accidental loss of control is soon exposed to be more.
After recognizing numerological patterns in the Bible verses that the killer leaves behind, Don and his team are able to track the killer's movements but are one step behind when a gripping twist brings the chase to an end.
Bank for the rich and powerful is robbed but the stolen contents of the safety deposit boxes are being liquidated and donated to charities, and it's up to Don and Charlie to uncover the true motivation behind the humanitarian thief.
Don feels responsible for the death of a participant in the Witness Protection Program after she is gunned down in her home.
Don and the team investigate the secret world of alternate-reality games after a man plunges to his death while participating in one such game. Amita's life is in danger when her hidden gaming ability becomes the key to tracking down the killer.
When a mega-heiress is abducted by an extremist group looking to punish her industrialist father, Don and the team rush to find her captors, but their attempt to save her takes a startling turn when they uncover the group's true motivation.
Charlie works to find an extremely rare comic that was stolen during a deadly robbery at a comic book convention.
Don and the team come under pressure when a former FBI subcontractor shoots an agent inside the FBI headquarters and takes one of their own as a hostage, leaving them with a severely restricted plan of action.
Charlie becomes the target of physical intimidation aimed at disrupting his work on the case of a missing investigative journalist.
Don and his team work to track down a serial rapist who is using his position as a police officer to lure his victims.
Don and the team take down an inner-city meth lab, but it is Don's FBI instinct that leads to the arrest of a bystander who is discovered to have a greater scheme in the works.
Don's old flame Robin Brooks returns to California to prosecute an incarcerated criminal, but when three witnesses involved in the case are murdered, Don and his team realize that the next victim may be Robin and must work to keep her safe.
The team searches for a motive after the family members of Clay Porter, Jr., a fugitive on the run for murder, are taken hostage by a gang of military thieves.
Mass poisoning at a cult compound leads the FBI team into a maze of old grudges and a complex murder plot.
The murder of a rapper puts Charlie to work analyzing the mathematics of the music business in the same week that Amita's parents come to town, and Megan has asked for a week off without discussing it with Don.
Don and Charlie find themselves in conflict over their differing beliefs as they investigate a case involving national security. Meanwhile, Megan faces a crisis of conscience and leaves the team.
Don and his team hunt for the killers of two rock climbers found in possession of a large diamond. Also, Charlie decides if he should try to get his FBI clearance reinstated, and a new agent joins the team.
The team investigates a pattern of increased ATM kidnappings when a woman who was abducted and forced to withdraw random amounts of money from her ATM is murdered. Also, Charlie meets the man who will decide the fate of his FBI security clearance.
When eight people, including two police officers, are executed in a coffee shop, an LAPD detective gets the team on the case, and they uncover a trail of blackmail, romance and corruption. Also, McGowan's investigation of Charlie and Don deepens.
Don and his team are called in to help a veteran FBI agent track down a con man who has eluded him for years. Also, Agent McGowan hands down his decision on Charlie's security clearance and Don's future with the FBI.
The team hunts a crew stealing high-end goods from a shipping service and looks to an employee with savant-like abilities to lead them to those behind the scheme. Also, when one of Don's men is killed on duty, he questions his faith in the FBI.
While on a date, David catches a disappearing act at a magic show but quickly becomes involved in the performance when the magician really vanishes.
The death of a family friend, who's a former pro-surfer, is ruled an accident. The team investigates, uncovering a startling connection to another crime.
When a passenger train collides with a freight train carrying toxic chemicals, Don, Charlie and the team begin to investigate if foul play was involved.
The bombing of an influential charity's headquarters forces the team to sift through various rumors about the true reach of the organization's power.
When a vigilante group goes after a known criminal mastermind, Charlie is forced to turn to his rival for help. Also, Don wrestles with his emotions towards embracing religion.
Don looks toward his newly found religious beliefs to help him contend with an escaped criminal bent on revenge.
The team has only four hours to stop a group of hijackers who take a bus full of Hollywood tourists hostage.
Feud between rival Chinese gangs leads to the kidnapping of an undercover agent and the re-appearance of the enigmatic Samuel Kraft.
Stolen pair of "kicks" leads the team into the world of sneaker collecting after a foreign Ambassador finds his prized pair missing.
When Robin's seemingly strong case against a weapons smuggler falls apart, the team decides to look into the jury who heard the case.
To stop a new drug from hitting the streets, Charlie devises a plan that could put Liz in harm's way.
When a super computer is the prime suspect in the death of cutting-edge scientist, the team must use new means to crack the case. Meanwhile, Charlie weighs a compelling job offer.
The team has only hours to investigate a last minute tip that could exonerate a dangerous mob boss on the eve of his execution. Meanwhile Charlie's attempt to help the CalSci basketball team break their incredible losing streak leads to some interesting outside help .
The investigation into a professor's death takes a dangerous turn when the team finds their lead suspect has ties to a radical animal rights group.
When the FBI is called in to investigate a series of home invasions, the team uses Charlie and his math skills to help profile the suspects, but when his calculations go awry during a raid, Don suffers a life-threatening injury.
Still feeling responsible for Don's near-fatal stabbing, Charlie puts his focus into tracking down an unnoticed serial killer, with the agents revisiting math theories from when Charlie first started working with the team to help solve the case.
Don and the team investigate a string of copycat bank robberies and zero in on disgraced FBI Agent Roger Bloom as a suspect when they discover he has been studying the files of some of the original bank heists.
When Amita is abducted, Don and the team's frantic search for her leads them to the delusional head of a cult, but it is up to a distraught Charlie to discover what the suspect's bizarre plans for her are.
Don and the team must protect high-profile activist Benjamin Polk at a political rally, but it soon becomes a manhunt when they search for a sniper trying to kill Polk. Also, Charlie awaits an answer from Amita about his marriage proposal.
When two FBI agents, part of a unit headed by Don's former mentor, are killed during a shootout with bank robbers, the team must investigate what exactly happened. Also, Charlie and Amita worry when Larry opts not to attend a conference in Geneva.
Don and his team are called in to investigate who is behind a deadly gambling ring that is running a high-stakes Russian roulette tournament. Also, Don and Charlie become concerned about Alan's financial health.
Don and the team investigate a series of murders which they realize are being copied from scenes out of a soon-to-be-released movie. Also, Larry leaves to embark on his personal adventure.
The team searches for a geneticist's daughter who they suspect was abducted by her unstable mother, but become more concerned when they think the young girl may be a clone. Also, Charlie and Amita talk about having kids, and Liz reveals a dark secret.
When strange, almost paranormal happenings are observed at a decommissioned air base, the spooky occurrences take on a decidedly different tone when the team is brought in to investigate the mystery of a dead woman found there.
The team conducts an undercover sting to locate a cyber crime lord, but the operation is foiled by a charming, brilliant hacker whose desire to take over the online black markets puts him in a dangerous online turf war that could lead to murder.
While tracking down a felon running a heroin ring inside a prison, Agent Ian Edgerton becomes a murder suspect when the informant he meets with ends up dead, sending a desperate Edgerton over the edge when he takes a member of Don's team hostage.
When robbers hit a diamond exchange and take hostages, Don and the team find an unlikely ally in convict John Buckley, who may help the team's investigation when they believe the men are copying Buckley's criminal strategies.
When the team foils a robbery of an armored car full of Federal Reserve money and recover bills that trace back to the infamous D.B. Cooper heist, they call on Agent Roger Bloom, who worked on the Cooper case, for help with the investigation.
Don and the team try their luck at investigating the theft of scratch-off lottery tickets, but the stakes are raised when one of the culprits killed at a botched robbery turns out to be a former lottery winner.
The team searches for a lost shipment of high-caliber firearms when one of the weapons is responsible for random killings throughout the city. Also, Charlie and Amita disagree on a wedding date while Don re-evaluates his relationship with Robin.
The team searches for a serial killer who is targeting men that solicit prostitutes. Also, Colby and Nikki deal with the aftermath of a car crash when they have an accident during the investigation.
The team gets a taste of the limelight when they search for jewels worth millions that have been stolen during an awards show broadcast. Also, Don revisits an old case that is haunting him, and Larry returns from his adventure in the desert.
The team investigates the deaths of two men who were part of a group of friends that had been sexually assaulted by a teacher when they were young boys. Also, Charlie and Amita get a fantastic job opportunity that could put a wrinkle in their wedding plans.
After Charlie and Amita get married and begin preparations for their London adventure, they put a slight hold on their wedded bliss when they assist the team in helping Don track down the whereabouts of his gun after it goes missing.